Determination of In Vitro Antioxidant, Antimicrobial Properties and COX-1 Enzyme Inhibitory Activity of Mentha Pulegium


Özet Görüntüleme: 90 / PDF İndirme: 49

Yazarlar

  • Recep Koçyiğit
  • Fatih Caglar Celikezen
  • İbrahim Halil Şahin
  • Oğuz Ayhan Kireççi
  • Mehmet Fırat
  • Nağihan ACAR

DOI:

https://doi.org/10.5281/zenodo.10430950

Anahtar Kelimeler:

Lamiaceae, antibiotic, analgesic, anti-inflammatory, herbal extract

Özet

People have used medicinal and aromatic plants and spices for centuries in order to treat diseases. Mentha pulegium is utilized as food in the world and in Turkiye and also a medicinal plant in traditional treatments. In this context, this study was carried out to examine the antioxidant and antimicrobial properties of the Mentha pulegium plant and its effects on cyclooxygenase-1 enzyme. While antioxidant properties were investigated spectrophotometrically by using 2,2-diphenyl-1-picrylhydrazyl, free radical test  and Cupric Reducing Antioxidant Capacity assay methods, antibiotic effect was determined by using disc diffusion method. The effects on cyclooxygenase-1 enzyme were determined colorimetrically using commercial kits. The results showed that Mentha pulegium plant had a significant antioxidant effect, but it did not have any antibiotic effect on Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Candida albicans strains. On the other hand, it exhibited a very weak inhibitory effect on the cyclooxygenase-1 enzyme. Consequently, the Mentha pulegium plant has an important antioxidant property and showed a very weak inhibitory effect on the cyclooxygenase-1 enzyme.

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Yayınlanmış

2023-12-26

Nasıl Atıf Yapılır

Koçyiğit, R., Celikezen, F. C., Şahin, İbrahim H., Kireççi, O. A., Fırat, M., & ACAR, N. (2023). Determination of In Vitro Antioxidant, Antimicrobial Properties and COX-1 Enzyme Inhibitory Activity of Mentha Pulegium. International Journal of Medicine and Occupational Health and Safety Sciences, 1(2), 111–118. https://doi.org/10.5281/zenodo.10430950

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